Support healthy immune cell activity today!
QTY - 30 Vegetarian Capsules
- Supports Healthy Immune Function*
- Supports the Body’s Defenses Against Seasonal Immune Challenges*
- Active Ingredient Beta-Glucan
Bock Nutritionals’s Immune-Up is refined to remove most impurities, including proteins and fats that can interfere with uptake and effectiveness.
Beta-glucan has been recognized for its support of immune system activity for centuries; and yeast-derived beta-glucan has become the subject of over 800 scientific studies to date. Bock Nutritionals Immune-Up contains concentrated 1,3/1,6 beta-glucan from the yeast Saccharomyces cerevisiae, a source known to support immune function. [2-4] Beta-glucan is produced by fungi, grains, seaweed, and yeast, but not by mammalian cells.[3-5] delivers 250 mg of whole glucan particle per capsule, providing beta 1,3/1,6 glucan—a unique complex carbohydrate purified from Saccharomyces cerevisiae (baker’s yeast).
It is natural, non-genetically modified (non-GMO), hypoallergenic, patented, and generally recognized as safe (GRAS). Taken orally, Immune-Up primes and mobilizes the cells that support the body's first-line immune response.*
Suggested Use: For ongoing immune support: Take 1 capsule daily, first thing in the morning or last thing at night (before or well after a meal), with a full 8 oz glass of water. For fast-acting immune support: Take up to 2 capsules per day, as above; or as directed by your healthcare practitioner.*
Servings Per Container: 30
Serving Size: 1 Capsule
|Ingredients||Amount Per Serving||% Daily Value|
|Whole Glucan Particle (providing beta-glucan naturally derived from Saccharomyces cerevisiae)||250 mg||**|
Other Ingredients: Dicalcium phosphate anhydrous, HPMC (capsule), stearic acid, magnesium stearate, silica, and medium-chain triglycerides.
- Tian J, Ma J, Wang S, et al. Increased expression of mGITRL on D2SC/1 cells by particulate β-glucan impairs the suppressive effect of CD4(+)CD25(+) regulatory T cells and enhances the effector T cell proliferation. Cell Immunol. 2011 May 10;270(2):183-7. [PMID: 21636079]
- 2. Feldman S, Schwartz HI, Kalman DS, et al. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. J Appl Res. 2009 MarchJune;9(1&2):30-42. http://jrnlappliedresearch.com/articles/Vol9Iss1/FeldmanVol9No1.pdf. Accessed September 9, 2011.
- 3. Driscoll M, Hansen R, Ding C, et al. Therapeutic potential of various beta-glucan sources in conjunction with anti-tumor monoclonal antibody in cancer therapy. Cancer Biol Ther. 2009 Feb;8(3):218-25. [PMID: 19106638]
- 4. Liang, J., D. et al. Enhanced clearance of a multiple antibiotic-resistant Staphylococcus aureus in rats treated with PGG-glucan is associated with increased leukocyte counts and increased neutrophil oxidative burst activity. Int J Immunopharmacol. 1998 Nov;20(11):595-614. [PMID: 9848393]
- 5. Vetvicka V. Glucan-immunostimulant, adjuvant, potential drug. World J Clin Oncol. 2011 Feb 10;2(2):115-9. [PMID: 21603320]
- Vetvicka V, Terayama K, Mandeville R, et al. Pilot study: orally-administered yeast ß1,3-glucan prophylactically protects against anthrax infection and cancer in mice. JANA. 2002;5(2):5-9. Reprint. http://www.ana-jana.org/Journal/journals/JANAVol52.pdf. Accessed August 21.
- 7. Natural Standard Database http://naturalstandard.com. Accessed July 23, 2011.
- Yan J, Allendorf DJ, Brandley B. Yeast whole glucan particle (WGP) beta-glucan in conjunction with antitumour monoclonal antibodies to treat cancer. Expert Opin. Biol Ther. 2005 May;5(5):691-702. [PMID: 15934844]
- 9. Qi C, Cai Y, Gunn L, et al. Differential pathways regulating innate and adaptive antitumor immune responses by particulate and soluble yeast-derived ß-glucans. Blood. 2011 Jun 23;117(25):6825-36. [PMID: 21531981]
- 10. Pelizon AC, Kaneno R, Soares AM, et al. Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae. Physiol Res. 2005;54(5):557-64. [PMID: 16238470]
- 11. Tsikitis V, Albina J, Reichner J. Beta-glucan affects leukocyte navigation in a complex chemotactic ingredient. Surgery. 2004 Aug;136(2):384-9. [PMID: 15300205]
- 12. Senoglu N, Yuzbasioglu MF, Aral M, et al. Protective effects of N-acetylcysteine and beta-glucan pretreatment on oxidative stress in cecal ligation and puncture model of sepsis. J Invest Surg. 2008 Sep-Oct;21(5):237-43. [PMID: 19160131]
- 13. Turnbull, JL, Patchen ML, Scadden DT. The polysaccharide, PGGglucan, enhances human myelopoiesis by direct action independent of and additive to early-acting cytokines. Acta Haematol. 1999;102(2):66-71. [PMID: 10529508]
- 14. Kournikakis B, Mandeville R, Brousseau P, et al. Anthrax-protective effects of yeast beta 1,3 glucans Med Gen Med. 2003 Mar 21;5(1):1. [PMID:12827062]